人星形胶质细胞(HA细胞)

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accegen
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2022-08-31 06:52

北京百奥创新科技有限公司

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北京百奥创新科技有限公司
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产品属性
产品说明
Product Name

Human Astrocytes

Product Code

HA

Cat.No

ABC-TC3969

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Astrocytes are a subtype of neuroglial cells in the mammalian brain and spinal cord. With the typical star-like morphology, human astrocytes generally have sparse organelles and several processes radiating from the central cell body. A single astrocyte could be associated with a number of neuronal synapses since each process shows extensive terminal branching. HA are the most explored non-neuronal cells in the brain under neurophysiological and neurodegenerative conditions.
星形胶质细胞是哺乳动物大脑和脊髓中神经胶质细胞的一种亚型。人类星形胶质细胞具有典型的星形形态,细胞器稀疏,多个突起从中心细胞体向外辐射。单个星形胶质细胞可能与许多神经元突触相关联,因为每个进程都表现出广泛的末端分支。血凝素是在神经生理学和神经退行性条件下探索最多的非神经元细胞。

Astrocytes Functions

Considered as full-fledged participants in brain circuitry and processing, human astrocytes provide a variety of functions at the cell level acting on the formation, maturation, and elimination of synapses, ionic homeostasis, clearance of neurotransmitters, regulation of extracellular space volume, and modulation of synaptic activity and plasticity. Astrocytes are involved in an incredible variety of processes so that a change in their characteristics will alter their contribution to neuronal functions. Some astrocytes that have vascular feet at the end of their processes take part in the forming of the blood-brain barrier (BBB).

Extensive researches about the specific role of HA during neuropathological conditions have been done, however, their mechanism of action and specific role in neurodegenerative conditions could not be concluded by existing findings.
星形胶质细胞功能
人类星形胶质细胞被认为是大脑回路和加工过程的成熟参与者,在细胞水平上提供多种功能,作用于突触的形成、成熟和消除、离子稳态、神经递质清除、细胞外空间体积的调节以及突触活性和可塑性的调节。星形胶质细胞参与各种各样的过程,因此其特征的改变将改变其对神经元功能的贡献。一些星形胶质细胞在其突起末端具有血管足,参与血脑屏障(BBB)的形成。
关于HA在神经病理中的具体作用已经有了大量的研究,但其在神经退行性疾病中的作用机制和具体作用尚不能通过现有的研究结果得出结论。

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

For research use only

Key Features

-Backed by AcceGen advanced technology
-Cryopreserved for highest viability and plating efficiency
-Quality-tested for accurate results

Product Type

Nervous Cells

Product Image

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