【产品形式】：艾美捷为您提供的【SHH，His】重组人音猬因子,His标签蛋白产品是是在大肠杆菌中重组表达的，是一条单链、非糖基化的多肽链，包含有183个氨基酸，分子量为20.7kDa。该人音猬因子，His标签重组蛋白的C末端融合了一个8个氨基酸的His标签，该蛋白最终由标准的色谱技术纯化出。

【背景资料】：Recombinant Human Sonic Hedgehog is part of a small group of secreted proteins that are vital for development in both vertebrates and invertebrates. 3 mammalian hedgehog genes (sonic，desert，Indian) share about 60% homology. The Human Sonic Hedgehog is 99% homologous to the mouse gene. Sonic HedgeHog is a protein that is vital in guding the early embryo. It has been associated as the major inductive signal in patterning of the ventral neural tube，the anterior-posterior limb axis，and the ventral somites. Sonic HedgeHog binds to the patched receptor，which functions in association with smoothened，to activate the transcription of target genes. In the absence of sonic HedgeHog，patched receptor represses the constitutive signaling activity of smoothened. Sonic HedgeHog also regulates another factor，the gli oncogene. Sonic HedgeHog intercellular signal is essential for a various patterning events during development: signal produced by the notochord that induces ventral cell fate in the

以色列ProSpec-Tany公司专注于细菌来源重组蛋白质生产。其独有细菌和哺乳动物表达和蛋白折叠技术使其成为国际一流科研级蛋白供应商。ProSpec-Tany是世界上能提供蛋白种类最多公司之一。领先生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。作为多家知名品牌代理，艾美捷与ProSpec一起为研究者们提供最好、最新细胞生物学研究工具而不断扩大产品及服务质量。更多特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看中国生命科学试剂产品评论网站。

点击【SHH，His】重组人音猬因子,His标签查看更详细产品说明，更多应用、储存、价格、货期等信息请致电400-6800-1454垂询Prospec中国区域授权总代理艾美捷科技有限公司。