| Background: | Thisgeneencodesareceptortyrosinekinase-likeorphan receptorthatmodulatesneuritegrowthinthecentralner voussystem.TheencodedproteinisaglycosylatedtypeIm embraneproteinthatbelongstotheRORsubfamilyofcells urfacereceptors.Itisapseudokinasethatlackscatalyticacti vityandmayinteractwiththenon-canonicalWntsignallin gpathway.Thisgeneishighlyexpressedduringearlyembryoni cdevelopmentbutexpressedatverylowlevelsinadulttissues.In creasedexpressionofthisgeneisassociatedwithB-cellchroniclymphocyticleukaemia.Alternativesplicingresultsin multipletranscriptvariantsencodingdifferentisoforms. |
| Applications: | ELISA,IHC |
| Nameofantibody: | ROR1 |
| Immunogen: | SyntheticpeptideofhumanROR1 |
| Fullname: | receptortyrosinekinase-likeorphanreceptor1 |
| Synonyms: | NTRKR1;dJ537F10.1 |
| SwissProt: | Q01973 |
| ELISARecommendeddilution: | 2000-5000 |
| IHCpositivecontrol: | HumanlungcancerandHumanprostatecancer |
| IHCRecommenddilution: | 25-100 |
