本公司提供科研CD40/TNFRSF5肿瘤坏死因子受体超家族成员5抗体，抗体质量可靠，订购CD40/TNFRSF5肿瘤坏死因子受体超家族成员5抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：肿瘤坏死因子受体超家族成员5抗体
英文名称：Anti-CD40/TNFRSF5
货号：bs-2929R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 30kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, Rb, dog, rat, pig, cow, chk
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul2008].Subcellular Location : Isoform I: Cell membrane; Single-pass type I membrane protein. Isoform II: Secreted.Tissue Specificity : B-cells and in primary carcinomas.Similarity : Contains 4 TNFR-Cys repeats.产品图片Antigen: bs-2929P, 0.2ug/100ul Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat-Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000; TMB(C-0024) staining; Read the data in MicroplateReader by 450nm.