天然麦醇溶蛋白/Native Gliadin
NativeGliadin Triticum Aestivum Grain

CATALOGUE NUMBER

PRO-2675

INTRODUCTION

Gliadin is a common substrate of transglutaminase, which generates neo-epitopes by deamidation of glutamine side chains. In the past, serologic tests for gliadin antibodies usually were not very precise and were not enough for accurate diagnosis due to missing deamidated epitopes within the authentic gliadin fraction traditionally used in diagnostic test kits. ProSpec's deamidated Gliadin isoform matches to the deamidated neo-epitopes, which in the natural antigen are formed by transglutaminase-mediated glutamine side chain deamidation.

DESCRIPTION

The native Gliadin Triticum Aestivum Grain is purified from wheat by protein chemical methods.

PHYSICAL APPEARANCE

Sterile Filtered clear solution.

FORMULATION

Gliadin is supplied in 20mM HEPES buffer pH-7.4 and 6M Urea.

STABILITY

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
Avoid multiple freeze-thaw cycles.

PURITY

Greater than 95.0% as determined by SDS-PAGE.

IMMUNOLOGICAL FUNCTIONS

1. Binds IgG and IgA-type human auto antibodies in sera of patients diagnosed with celiac disease.
2. Immunodot analysis with positive/negative samples.

APPLICATIONS

Western blot with patient sample.

USAGE

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

PRO-2675	天然麦醇溶蛋白	Native Gliadin	NativeGliadin Triticum Aestivum Grain
pro-114	重组小麦麦醇溶蛋白	Wheat Gliadin	Recombinant Wheat Gliadin Gamma 18.6kD
PRO-2147	重组小麦麦醇溶蛋白Alpha	Wheat Gliadin Alpha	Recombinant Wheat Gliadin Alpha
PRO-2148	重组小麦麦醇溶蛋白Gamma	Wheat Gliadin Gamma	Recombinant Wheat Gliadin Gamma