货号 PAab01499
蛋白别名 IGA antibody, MB1
蛋白介绍
Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src- family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
产品描述
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using PAab01499( CD79A Antibody) at dilution of 1:200
Western blot
Raji cells were subjected to SDS PAGE followed by western blot with PAab01499(CD79A antibody) at dilution of 1:1000(本抗体仅供体外科研用途,不可用于临床诊断!)
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