关键词：AMPKβ2抗体;腺苷单磷酸活化蛋白激酶β2抗体;腺苷单磷酸活化蛋白激酶β2;AMPKβ2;ABP57261

中文名称：腺苷单磷酸活化蛋白激酶β2多克隆抗体/AMPKβ2 Polyclonal Antibody

英文名称：AMPKβ2 Polyclonal Antibody

产品说明书：http://www.abbkine.cn/datasheet/ABP57261.pdf

产品描述：兔抗-腺苷单磷酸活化蛋白激酶β2 多克隆抗体

The protein encoded by PRKAB2 (protein kinase AMP-activated non-catalytic subunit beta 2) is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR， key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for PRKAB2.

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