FITC标记的多药耐药相关蛋白4抗体

¥2980
LMAIBio
中国/美国/欧洲
2022-09-15 08:19

上海联迈生物工程有限公司

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产品属性
产品说明
FITC标记的多药耐药相关蛋白4抗体
英文名称Anti-MRP4/ABCC4/FITC
中文名称FITC标记的多药耐药相关蛋白4抗体
别 名ABCC 4; ABCC4; ATP binding cassette sub family C (CFTR/MRP) member 4; ATP binding cassette sub family C member 4; bA464I2.1 (ATP binding cassette, sub-family C (CFTR/MRP) member 4); bA464I2.1; Canalicular multispecific organic anion transporter; Canalicular multispecific organic anion transporter ABC superfamily; EST170205; MOAT B; MOATB; MRP 4; MRP/cMOAT related ABC transporter; Multi specific organic anion transporter B; Multidrug resistance associated protein 4; OTTHUMP00000018560; MRP4_HUMAN.
规格价格100ul/2980元 购买 大包装/询价
说 明 书100ul
研究领域信号转导
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Guinea Pig,
产品应用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量149kDa
性 状Lyophilized or Liquid
浓 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human MRP4
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍background:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. [provided by RefSeq, Jul 2008].

Function:
May be an organic anion pump relevant to cellular detoxification.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Widely expressed, with particularly high levels in prostate, but is barely detectable in liver.

Similarity:
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. 
Contains 2 ABC transmembrane type-1 domains. 
Contains 2 ABC transporter domains.

Database links:

Entrez Gene: 10257 Human

Entrez Gene: 239273 Mouse

Omim: 605250 Human

SwissProt: O15439 Human

Unigene: 508423 Human

Unigene: 40537 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.