本公司提供科研CREPT肿瘤高表达细胞周期相关蛋白抗体，抗体质量可靠，订购CREPT肿瘤高表达细胞周期相关蛋白抗体请联系在线客服或者销售人员。
抗体参数如下>>>>
中文名称：肿瘤高表达细胞周期相关蛋白抗体
英文名称：Anti-CREPT
货号：bs-9971R
抗体来源：兔
克隆类型：多克隆
蛋白分子量：predicted molecular weight: 37kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat
测试应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
产品背景介绍：Interacts with phosphorylated C-terminal heptapeptiderepeat domain (CTD) of the largest RNA polymerase II subunitPOLR2A, and participates in dephosphorylation of the CTD.Transcriptional regulator which enhances expression of CCND1.Promotes binding of RNA polymerase II to the CCDN1 promoter and tothe termination region before the poly-A site but decreases itsbinding after the poly-A site. Prevents RNA polymerase II fromreading through the 3' end termination site and may allow it to berecruited back to the promoter through promotion of the formationof a chromatin loop. Also enhances the transcription of a number ofother cell cycle-related genes including CDK2, CDK4, CDK6 andcyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.