重组人POMGNT1(N-乙酰氨基葡萄糖-甘露糖转移酶1) 产品官方链接

面议
百奥莱博
北京
2024-06-20 14:12

北京百奥莱博科技有限公司

VIP会员
王欣
18518407031
18518407031@163.com
570202610
北京百奥莱博科技有限公司
产品属性
货号JN0713
规格10μg | 50μg | 500μg | 1mg
产品说明
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Leu59-Thr660在C端含有His标签。

POMGNT1质量控制:>95%(还原性SDS-PAGE)

POMGNT1制剂:液体

POMGNT1保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。

关于POMGNT1
Protein O-Linked-Mannose β-1 2-N-Acetylglucosaminyltransferase 1 (POMGNT1) belongs to the Glycosyltransferase 13 family. Amino acid residues between 299-311 are important for both protein expression and enzymatic activity. The minimal catalytic domain is located between positions 299-651. It is suggested that the stem domain of the soluble form is unnecessary for activity, but that some amino acids play a crucial role in the membrane-bound form. Defects in POMGNT1 are the cause of muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies type A3 (MDDGA3).