重组人N-糖基化酶 产品官方链接

面议
百奥莱博
北京
2024-06-20 14:12

北京百奥莱博科技有限公司

VIP会员
王欣
18518407031
18518407031@163.com
570202610
北京百奥莱博科技有限公司
产品属性
货号JN1926
规格10μg | 50μg | 500μg | 1mg
产品说明
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Gly345在N端带有GST标签。

DNA Lyase质量控制:>95%(还原性SDS-PAGE)

DNA Lyase制剂:液体

DNA Lyase保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。

关于DNA Lyase
Human N-Glycosylase/DNA Lyase(OOG1) is a DNA repair enzyme, which belongs to the type-1 OGG1 family. OOG1 incises DNA at 8-oxoG residues, and excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damage DNA. It has a β-lyase activity that nicks DNA 3’ to the lesion. OOG1 together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells. The OGG1 gene mutations may be caused Renal cell carcinoma.