重组人白介素IL-15(白细胞介素15) 产品官方链接

面议
百奥莱博
北京
2024-06-20 14:12

北京百奥莱博科技有限公司

VIP会员
王欣
18518407031
18518407031@163.com
570202610
北京百奥莱博科技有限公司
产品属性
货号JN0336
规格10μg | 50μg | 500μg | 1mg
产品说明
本品由我们的大肠杆菌表达系统制备,目的基因编码的Asn49-Ser162表达纯化而来。

IL-15质量控制:>95%(还原性SDS-PAGE)。

IL-15制剂:冻干品

IL-15保存
冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天。
复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。

IL-15复溶
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存,避免反复冻融。

关于IL-15
Human Interleukin 15 (IL-15) is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL15 receptor (IL-15RA) with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor. IL-15 is structurally and functionally related to IL-2. Both cytokines share some subunits of receptors, allowing them to compete for and negatively regulate each other's activity. The number of CD8+ memory T cells is controlled by a balance between IL-15 and IL-2. Despite their many overlapping functional properties, IL-2 and IL-15 are, in fact, quite distinct players in the immune system. IL-15 is constitutively expressed by a wide variety of cell types and tissues, including monocytes, macrophages and DCs. Mature Human IL-15 shares 70% amino acid sequence identity with Mouse and Rat IL-15.