重组人检查点蛋白(HUS1) 产品官方链接

面议
百奥莱博
北京
2024-06-20 14:12

北京百奥莱博科技有限公司

VIP会员
王欣
18518407031
18518407031@163.com
570202610
北京百奥莱博科技有限公司
产品属性
货号JN0900
规格10μg | 50μg | 500μg | 1mg
产品说明
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Ser280在N端含有His标签。

HUS1质量控制:>95%(还原性SDS-PAGE)

HUS1制剂:液体

HUS1保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。

关于HUS1
Checkpoint protein HUS1 is a member of the HUS1 family, members of which are shuttled between the nucleus and cytoplasm. HUS1 is expressed in many tissues. HUS1 is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex involved in arresting the cell cycle in response to DNA damage. DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. HUS1 binds with Rad9 and Rad1 to form the 9-1-1 (RAD9-RAD1-HUS1) complex, which localizes to DNA lesions and promotes DNA damage signaling and repair or apoptosis and cell cycle arrest.