重组人纽蛋白(黏着斑蛋白)(Vinculin蛋白) 产品官方链接

面议
百奥莱博
北京
2024-06-20 14:12

北京百奥莱博科技有限公司

VIP会员
王欣
18518407031
18518407031@163.com
570202610
北京百奥莱博科技有限公司
产品属性
货号JN2034
规格10μg | 50μg | 500μg | 1mg
产品说明
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Pro2-Gln1066表达纯化得来。

Vinculin质量控制:>95%(还原性SDS-PAGE)

Vinculin制剂:冻干品

Vinculin保存
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。

Vinculin复溶
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。

关于Vinculin
Vinculin is a focal adhesion and cytoskeletal protein that distributed mainly at cell-cell junctions and cell-extracellular matrix (ECM) adhesion that belongs to the Vinculin/α-Catenin family. Vinculin is an Actin-binding protein and component of the Actin-Linking Functional module that senses and feels the mechanical properties of the extracellular environment. Vinculin is also a key factor that couples, transmits, transduces, and regulates mechanical force between the cytoskeleton and adhesion receptors. Vinculin generally forms two structural states, an open (active) and closed (inactive) state, which are controlled by conformational interaction(s) between the head and tail domains. Vinculin is involved in the mechano-chemical signal transmission of cells by binding to a variety of focal adhesion or cytoskeletal proteins, and plays important roles in cell adhesion, extension, motion, proliferation and survival.