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| 货号 | Z17292 |
| 规格 | 50μl | 100μl | 150μl |
| 抗体名称 | Anti-FKBP1A/1B Antibody |
| 指标别名 | FKBP1A;FKBP1;FKBP12;FKBP1A;FKBP52 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,IHC,FCM,ELISA |
| 基因名称 | FKBP1A/FKBP1B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human FKBP1A/1B recombinant protein (Position:M1-H88). |
| 实际分子量 | 15KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Peptidyl-prolyl cis-trans isomerase FKBP1A/1B is an enzyme that in humans is encoded by the FKBP1A/1B gene.The protein encoded by this gene is a member of the immunophilin protein family,which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking.The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin.It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor.It also interacts with multiple intracellular calcium release channels,and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor.In mouse,deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.Multiple alternatively spliced variants,encoding the same protein,have been identified.The human genome contains five pseudogenes related to this gene,at least one of which is transcribed. |
| Uniprot ID | P62942/P68106 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
| 基因名全称 | FKBP prolyl isomerase 1A/B |
| 蛋白名全称 | Peptidyl-prolyl cis-trans isomerase FKBP1A/1B |
| 推荐稀释比 | Western blot(WB) 1:500～2000 (ELISA)： 1:100～1000 Flow cytometry (FCM) 1～3μg/1×106 cells Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
