| 抗体名称 | Anti-HPSE Antibody |
| 指标别名 | Endo glucoronidase;HEP;heparanase;Heparanase 1;HPA;Hpa1;HPR1;HPSE;HPSE1;HSE1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | IHC,WB |
| 基因名称 | HPSE |
| 抗体来源 | Rabbit |
| 免疫原 | Synthesized peptide derived from human HPA1 |
| 计算分子量 | 61KD |
| 成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| 纯化方式 | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
| 背景资料 | Heparanase,also known as HPSE,is an enzyme that acts both at the cell-surface and within the extracellular matrix to degrade polymeric heparan sulfate molecules into shorter chain length oligosaccharides.Heparanase is an endo-beta-D-glucuronidase capable of cleaving heparan sulfate and has been implicated in inflammation and tumor angiogenesis and metastasis.The successful penetration of the endothelial cell layer that lines the interior surface of blood vessels is an important process in the formation of blood borne tumour metastases.Heparan sulfate proteoglycans are major constituents of this layer and it has been shown that increased metastatic potential corresponds with increased heparanase activity for a number of cell lines. |
| Uniprot ID | Q9Y251 |
| 基因名全称 | Heparanase |
| 蛋白名全称 | Heparanase |
| 推荐稀释比 | IHC-p 1:50~200, WB 1:500~2000 |