| 货号 | Z26582 |
| 规格 | 50μl | 100μl | 150μl |
| 抗体名称 | Anti-SGT1/ECD Antibody |
| 指标别名 | ECD;GCR2;HSGT1;Protein ecdysoneless homolog;Protein SGT1;SGT1;Suppressor of GCR2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,FCM,ELISA |
| 基因名称 | ECD |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human ECD recombinant protein (Position:L50-N632). |
| 实际分子量 | 73KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Protein SGT1 is a protein that in humans is encoded by the ECD gene.Regulator of p53/TP53 stability and function.Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP.May be involved transcriptional regulation.In vitro has intrinsic transactivation activity enhanced by EP300.May be a transcriptional activator required for the expression of glycolytic genes.Involved in regulation of cell cycle progression.Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins.The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex.May play a role in regulation of pre-mRNA splicing. |
| Uniprot ID | O95905 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | ecdysoneless cell cycle regulator |
| 蛋白名全称 | Protein ecdysoneless homolog |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 |
