| 抗体名称 | Anti-SRC3/NCOA3 Antibody |
| 指标别名 | ACTR;AIB 1;AIB1;CBP interacting protein;KAT13B;NCoA 3;NCOA3;nuclear receptor coactivator 3;pCIP;SRC 3;SRC3;SRC3/NCOA3;TRAM 1;TRAM1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | IHC,ELISA |
| 基因名称 | NCOA3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthesized peptide derived from human NCoA-3. |
| 计算分子量 | 155KD |
| 成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| 纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | The NCOA3 (also known as nuclear receptor coactivator 3 isoform a) is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions in a hormone-dependent fashion.The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex.NCOA3 probably acts via remodeling of chromatin and is involved in the coactivation of different nuclear receptors,such as for steroids (GR and ER),retinoids (RARs and RXRs),thyroid hormone (TRs),vitamin D3 (VDR) and prostanoids (PPARs).NCOA3 is also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit.NCOA3 may be associated with diseases such as breast cancer and meningothelial meningioma.Anti-NCOA3 Antibody is useful for researchers interested in cancer research,chromatin binding,transcription coactivator activity,Immunology,and Nuclear Signaling research. |
| Uniprot ID | Q9Y6Q9 |
| 基因名全称 | Nuclear receptor coactivator 3 |
| 蛋白名全称 | Nuclear receptor coactivator 3 |
| 推荐稀释比 | IHC 1:100～1:300
ELISA 1:40000 |
