| 抗体名称 | Anti-Vitronectin/VTN Antibody |
| 指标别名 | S protein;Serum spreading factor;V75;vitronectin;VN;VNT;VTN |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | VTN |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human Vitronectin(441-455aa GDKYYRVNLRTRRVD),identical to the related rat and mouse sequences. |
| 实际分子量 | 54KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Vitronectin(VTN)also known as complement S-protein,serum spreading factor and somatomedin B is a protein that in humans is encoded by the VTN gene.The protein encoded by this gene is a member of the pexin family.Vitronectin is an abundant glycoprotein found in serum and the extracellular matrix and promotes cell adhesion and spreading,inhibits the membrane-damaging effect of the terminal cytolytic complement pathway,and binds to several serpin serine protease inhibitors.Vitronectin is a 75kDa glycoprotein,consisting of 459 amino acid residues.By use of high resolution fluorescence in situ hybridization(FISH),Fink et al.(1992) mapped the VTN gene to 17q11.The localization was confirmed by cohybridization with a centromere-specific alphoid probe.About one-third of the protein's molecular mass is composed of carbohydrates.It is a secreted protein and exists in either a single chain form or a clipped,two chain form held together by a disulfide bond.Vitronectin has been speculated to be involved in hemostasis and tumor malignancy. |
| Uniprot ID | P04004 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | vitronectin |
| 蛋白名全称 | Vitronectin(VN) |
| 推荐稀释比 |
Western blot(WB) 1:500～2000 |
