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| 货号 | Z30272 |
| 规格 | 50μl | 100μl | 150μl |
| 抗体名称 | Anti-CHAT Antibody |
| 指标别名 | CHAT;CHOACTase;Choline acetylase;choline acetyltransferase;Choline O acetyltransferase;CMS1A;CMS1A2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | CHAT |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human CHAT recombinant protein (Position:D446-R652).Human CHAT shares 88.4% and 87% amino acid (aa) sequence identity with mouse and rat CHAT,respectively. |
| 实际分子量 | 83KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Choline acetyltransferase (commonly abbreviated as ChAT,but sometimes CAT) is a transferase enzyme responsible for the synthesis of the neurotransmitter acetylcholine.In humans,the choline acetyltransferase enzyme is encoded by the CHAT gene.This gene product is a characteristic feature of cholinergic neurons,and changes in these neurons may explain some of the symptoms of Alzheimer's disease.Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment.Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea.Multiple transcript variants encoding different isoforms have been found for this gene,and some of these variants have been shown to encode more than one isoform. |
| Uniprot ID | P28329 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
