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| 货号 | Z30333 |
| 规格 | 50μl | 100μl | 150μl |
| 抗体名称 | Anti-Complement C5 Antibody |
| 指标别名 | C5;Complement C5;complement component 5;CPAMD4 |
| 克隆性 | Polyclonal |
| 检验物种 | mouse,rat |
| 应用范围 | WB,FCM,ELISA |
| 基因名称 | C5 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived mouse C5 recombinant protein (Position:Q19-D294). |
| 实际分子量 | 75KD/115KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Complement component 5 is a protein that in humans is encoded by the C5 gene.This gene encodes a component of the complement system,a part of the innate immune system that plays an important role in inflammation,host homeostasis,and host defense against pathogens.The encoded preproprotein is proteolytically processed to generate multiple protein products,including the C5 alpha chain,C5 beta chain,C5a anaphylatoxin and C5b.The C5 protein is comprised of the alpha and beta chains,which are linked by a disulfide bridge.Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin,which possesses potent spasmogenic and chemotactic activity,and the C5b macromolecular cleavage product,a subunit of the membrane attack complex (MAC).Mice with a homozygous mutation in this gene exhibit impaired bone fracture healing and an enhanced inflammatory response in an allergic lung disease model. |
| Uniprot ID | P06684 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | hemolytic complement |
| 蛋白名全称 | Complement C5 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Flow cytometry (FCM) 1～3μg/1×106 cells (ELISA)： 1:100～1000 |
