| 抗体名称 | Anti-Complement factor B/CFB Antibody (Clone#26C16) |
| 指标别名 | BF;BFD;C3/C5 convertase;CFAB;CFB;Complement factor B;FB;FBI12;GBG;Glycine rich beta glycoprotein;H2 Bf;PBF2;Properdin factor B |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | CFB |
| 克隆号 | 26C16 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human Complement factor B |
| 实际分子量 | 100KD |
| 成分 | Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol,0.5mg/mL BSA. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Complement factor B is a protein that in humans is encoded by the CFB gene.This gene encodes complement factor B,a component of the alternative pathway of complement activation.Factor B circulates in the blood as a single chain polypeptide.Upon activation of the alternative pathway,it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb.The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase.Bb is involved in the proliferation of preactivated B lymphocytes,while Ba inhibits their proliferation.This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6.This cluster includes several genes involved in regulation of the immune reaction.Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration.The polyadenylation site of this gene is 421bp from the 5' end of the gene for complement component 2. |
| Uniprot ID | P00751 |
| 基因名全称 | Complement factor B|EC 3.4.21.47|C3/C5 convertase|Glycine-rich beta glycoprotein|GBG|PBF2|Properdin factor B [Cleaved into:Complement factor B Ba fragment;Complement factor B Bb fragment] |
| 蛋白名全称 | Complement factor B |
| 推荐稀释比 |
Western blot (WB) 1:500～2000 |
