| 货号 | Z34934 |
| 规格 | 50μl | 100μl | 150μl |
| 抗体名称 | Anti-MAP Kinase,Activated(Diphosphorylated ERK-1&2) Antibody (Clone#MAPK-YT) |
| 指标别名 | ERK;ERK 2;ERK1/2;ERK2;ERT1;MAP kinase 1;MAP kinase 2;MAP kinase isoform p42;MAPK 1;MAPK 2;MAPK1;MAPK2;p40;p41;p41mapk;p42 MAPK;P42MAPK;PRKM1;PRKM2 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat,yeast |
| 应用范围 | WB,IHC,ICC |
| 基因名称 | MAPK1;MAPK3 |
| 克隆号 | MAPK-YT |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | A synthetic peptide containing 11 amino acids,HTGFLTpEYpVAT,corresponding to the phosphorylated form of ERK-activation loop conjugated to KLH. |
| 实际分子量 | 43KD |
| 成分 | 200μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Ascites |
| 浓度 | 200μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | In mammalian cells,a variety of extracellular stimuli generate intracellular signals that converge on a limited number of so-called mitogen-activated protein(MAP) kinase pathways.The central core of each MAP kinase(MAPK) pathway is a conserved cascade of 3 protein kinases:an activated MAPK kinase kinase(MAPKKK) phosphorylates and activates a specific MAPK kinase(MAPKK),which then activates a specific MAPK.Mek1/2 MAPK kinases are essential for mammalian development,homeostasis,and Raf-induced hyperplasia.Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome. |
| Uniprot ID | P28482 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | mitogen-activated protein kinase 1;mitogen-activated protein kinase 3 |
| 蛋白名全称 | Mitogen-activated protein kinase 1;Mitogen-activated protein kinase 3 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
