产品编号: KMP2273 产品名称: Human CD30 Protein, His Tag, Avi Tag 中文名称: 重组人CD30蛋白 中文全称: 重组人肿瘤坏死因子受体8蛋白 关键词: 肿瘤坏死因子受体8, Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30, CD30, TNFRSF8, Human CD30 Protein, His Tag, Avi Tag, Recombinant Protein, KMP2273 物种: Human 宿主: HEK293 Cells 规格: 50ug, 100ug, 200ug 纯化方式: Affinity purification 纯度: >95% as determined by SDS-PAGE 内毒素水平: <1.0 EU/ug determined by the LAL method 缓冲体系: 20mM PB, 150mM NaCl, pH7.4 Uniprot: P28908 SDS-PAGE: KMP2273 SDS-PAGE image1.png 功能: Receptor for TNFSF8/CD30L . May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B . 产品背景: CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody responses. CD30 is expressed by activated, but not by resting, T and B cells. Aberrant expression of CD30 by mastocytosis mast cells and interaction with its ligand CD30L(CD153) appears to play an important role in the pathogenesis and clinical presentation of systemic mastocytosis. CD30 has been considered as a specific diagnostic biomarker of anaplastic large cell lymphoma(ALCL) and classical Hodgkin lymphoma(cHL). CD30 is also a biomarker used for targeted therapy by an antibody–drug conjugate. 保存条件: Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. 运输条件: In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form. 说明: This product is for research use only. 官网链接: http://www.kmdbioscience.cn/ 参考文献: 1.Cell 73:1349-1360 (1993) 2.J. Biol. Chem. 272:2042-2045 (1997)