产品编号: KMP2344 产品名称: Mouse CD134 Protein, Fc Tag 中文名称: 重组鼠CD134蛋白 中文全称: 重组鼠肿瘤坏死因子受体超家族成员4蛋白 关键词: 肿瘤坏死因子受体超家族成员4, Tumor necrosis factor receptor superfamily member 4, ACT35 antigen, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, TNFRSF4, OX40, CD134, Txgp1, Mouse CD134 Protein, Fc Tag, Recombinant Protein, KMP2344 物种: Mouse 宿主: HEK293 Cells 规格: 50ug, 100ug, 200ug 纯化方式: Affinity purification 纯度: >95% as determined by SDS-PAGE 内毒素水平: <1.0 EU/ug determined by the LAL method 缓冲体系: PBS, pH7.4 Uniprot: P43488 SDS-PAGE: KMP2344 SDS-PAGE image1.png 功能: Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production. 产品背景: OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand(OX40L) will occur when activated T cells bind to professional antigen-presenting cells(APCs). The T-cell functions, including cytokine production, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases. 保存条件: Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. 运输条件: In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form. 说明: This product is for research use only. 官网链接: http://www.kmdbioscience.cn/ 参考文献: