产品编号: KMP2424 产品名称: Human CD357 Protein, Fc Tag 中文名称: 重组人CD357蛋白 中文全称: 重组人肿瘤坏死因子受体超家族成员 18蛋白 关键词: 肿瘤坏死因子受体超家族成员 18, Tumor necrosis factor receptor superfamily member 18, Glucocorticoid-induced TNFR-related protein, Tnfrsf18, AITR, CD357, GITR-D, TNFRSF18, Human CD357 Protein, Fc Tag, Recombinant Protein, KMP2424 物种: Human 宿主: HEK293 Cells 规格: 50ug, 100ug, 200ug 纯化方式: Affinity purification 纯度: >95% as determined by SDS-PAGE 内毒素水平: <1.0 EU/ug determined by the LAL method 缓冲体系: PBS, pH7.4 Uniprot: Q9Y5U5 SDS-PAGE: KMP2424 SDS-PAGE image1.png 功能: Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. 产品背景: Tumor necrosis factor receptor superfamily member 18(Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA、isformB and isformC is single-pass type I membrane protein and isformD is a secreted protein. The protein is the receptor for TNFSF18.It seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. It mediated NF-kappa-B activation via the TRAF2/NIK pathway.It binds to TRAF1, TRAF2, and TRAF3, but not TRAF5 and TRAF6 and binds through its C-terminus to SIVA1/SIVA.It preferentially expressed in activated T lymphocytes and up-regulated in peripherical mononuclear cells after antigen stimulation/lymphocyte activation. 保存条件: Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles. 运输条件: In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form. 说明: This product is for research use only. 官网链接: http://www.kmdbioscience.cn/ 参考文献: