| 中文名称 | 鸡脂联素(Adiponectin)ELISA检测试剂盒 |
| 英文名称 | Chicken Adiponectin ELISA Kit |
| 别名 | ACDC; Acrp30; ACRP30ADPN; adipocyte, C1Q and collagen domain containing; AdipoQ; ADIPQTL1; apM-1; APM1APM-1; C1q and collagen domain-containing protein; GBP28apM1; Gelatin-binding protein |
| 储存条件 | 保存在2-8℃,6个月。 |
| 规格 | 96T ; 48T |
| 运输条件 | 冷藏运输 |
| 检测目标 | Adiponectin |
| 样品类型 | 血清/血浆/细胞培养上清 |
| 反应性 | Chicken |
| 应用 | ELISA |
| 定量/定性 | 定量检测 |
| 精密度 | 板内,板间变异系数均<10% |
| 回收率 | 80%-120% |
| 疾病系列 | 糖尿病研究相关因子 ; 骨关节炎相关因子 ; 慢阻肺COPD研究相关因子 ; 冠心病研究相关因子 ; 骨质疏松症研究相关因子 ; 肥胖研究相关因子 ; 系统性红斑狼疮相关因子 ; 哮喘相关因子 ; 心血管疾病相关因子 |
| 研究领域 | 信号传导 ; 新陈代谢 ; 心血管 ; 干细胞 ; 神经学 ; 肿瘤&癌症 |
| 试剂盒类型 | 传统ELISA试剂盒 |
| 背景说明 | Adipose cells produce and secrete numerous physiologically important proteins, such as lipoprotein lipase (LPL), leptin and adiponectin protein of 30 kDa. Adiponectin is a circulating protein that is secreted exclusively by differentiated adipocytes. During adipocyte differentiation, mRNA levels of Adiponectin have been shown to be induced over 100-fold. Studies indicate that Adiponectin enhances the ability of sub-physiological levels of insulin to suppress glucose production, thus linking adipose tissue to whole body glucose regulation. Adiponectin function appears to be regulated by phosphatidylinositol-3-kinase (PI3-K) since Adiponectin secretion is blocked by pharmacologic inhibitors of this kinase. mRNA levels of Adiponectin have been shown to be significantly reduced in adipose tissue of obese patients with Type 2 diabetes relative to control subjects. Structural similarities to TNFalpha suggests that Adiponectin may play a role in pathogenesis of insulin resistance in Type 2 diabetes. Because Adiponectin is down-regulated in various forms of obesity and its structural similarity to TNFalpha, it is currently being investigated as an important regulator of whole body energy homeostasis. |
| 单位 | 盒 |