| 基因名 | DDB2 |
| 别名 | / |
| 全名 | damage-specific DNA binding protein 2，48kDa |
| 英文名称 | Recombinant Human DDB2 Protein |
| 中文名称 | 重组人DDB2蛋白 |
| 规格 | 1mg ; 100ug ; 50ug ; 10ug |
| 外观(性状) | Powder: Lyophilized from a 0.2 μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, 1mM DTT, PH7.2-8.0. (Or liquid with 5% glycerol.) |
| 纯度 | ≥85% by SDS-PAGE. |
| 储存条件 | Reconstituted protein solution can be stored at 4-7°C for 1-2 weeks, stored at < -20°C for 1 year. |
| 运输条件 | 冷藏运输 |
| 浓度 | 1mg/ml by SDS-PAGE. |
| Swiss Prot | Q92466 |
| Gene ID | 1643 |
| 分子量 | 38kDa |
| 区间范围 | 1-342aa |
| 背景说明 | This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] |
| 应用 | Immunology research |
| 来源 | E.coli |
| 纯化方法 | NI-NTA affinity purification |
| 溶剂 | Reconstituted protein solution can be diluted with distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. (It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water.) |
| 内毒素 | Not measured |
| 生物活性 | NO |
| 标签信息 | With a 6×His tag at the N/C-terminus. |
| 单位 | 支 |
| 属性分类 | 重组抗原 |
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