| 别名 | g gamma-1 chain C region;IGHG1 |
| 英文名称 | Recombinant Human IgG1 Fc/Ig gamma-1 chain C region/IGHG1 |
| 中文名称 | Recombinant Human IgG1 Fc/Ig gamma-1 chain C region/IGHG1 |
| 规格 | 10ug ; 50ug ; 500ug ; 1mg |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | 冷藏运输 |
| 背景说明 | As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta，Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells，and constitutes 75% of serum immunoglobulins in humans.IgG antibodies protect the body against the pathogens by agglutination and immobilization，complement activation，toxin neutralization，as well as the antibody-dependent cell-mediated cytotoxicity (ADCC).IgG tetramer contains two heavy chains (50 kDa ) and two light chains (25 kDa) linked by disulfide bonds，that is the two identical halves form the Y-like shape.IgG is digested by pepsin proteolysis into Fab fragment (antigen-binding fragment) and Fc fragment (crystallizable fragment).IgG1 is most abundant in serum among the four IgG subclasses (IgG1，2，3 and 4) and binds to Fc receptors (FcγR ) on phagocytic cells with high affinity. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
