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| 规格编号 | 规格 | 库存 | 价格 |
|---|---|---|---|
| P00478-10ug | 10ug | 现货 | 520.00 |
| P00478-50ug | 50ug | 现货 | 1196.00 |
| P00478-500ug | 500ug | 现货 | 5980.00 |
| P00478-1mg | 1mg | 现货 | 7920.00 |
| 别名 | Diphtheria toxin receptor; DTR;HEGFL; heparin-binding EGF-like growth factor; DTS; DTSF; heparin-binding epidermal growth factor; proheparin-binding EGF-like growth factor; HB-EGF; pro HB-EGF |
| 英文名称 | Recombinant Human HB-EGF/proHB-EGF/Heparin Binding EGF like Growth Factor |
| 中文名称 | Recombinant Human HB-EGF/proHB-EGF/Heparin Binding EGF like Growth Factor |
| 规格 | 10ug ; 50ug ; 500ug ; 1mg |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS， pH 7.4. |
| 溶解性 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C， stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | 冷冻运输 |
| Swiss Prot | Q99075 |
| 分子量 | 15.1 KDa |
| 表观分子量 | 16-27 KDa， reducing conditions |
| 区间范围 | Leu20-Leu148 |
| 背景说明 | Heparin-binding EGF-like growth factor (HB-EGF) is a 12-16 kDa member of the epidermal growth factor (EGF) family. It possesses an EGF-like domain， and a heparin-binding motif. Mature HB-EGF is a soluble peptide that arises from proteolytic processing of the transmembrane form. Human HB-EGF shows 76% and 73% aa sequence identity with rat and mouse HB-EGF， respectively. It is required for normal cardiac valve formation and normal heart function， promotes smooth muscle cell proliferation. It may be involved in macrophage-mediated cellular proliferation; it is mitogenic for fibroblasts， but not endothelial cells. HB-EGF classified as a group 2 ErbB ligand based on its ability to activate both the EGF/ErbB1 and ErbB4 receptors. Activity associated with ErbB4 binding appears to be limited to non-mitogenic actions， while EGFR binding induces both mitogenic and non-mitogenic activity. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | < 1 EU/μg as determined by LAL test. |
| 标签信息 | C-6His |
| 单位 | 支 |
