| 别名 | VEGFR2;VEGF R2;Vascular endothelial growth factor receptor 2;KDR;VEGFR-2;Fetal liver kinase 1;FLK-1;Kinase insert domain receptor;Protein-tyrosine kinase receptor flk-1 |
| 英文名称 | Recombinant Mouse VEGF R2/VEGF Receptor 2/FLK-1/KDR |
| 中文名称 | Recombinant Mouse VEGF R2/VEGF Receptor 2/FLK-1/KDR |
| 规格 | 10ug ; 50ug ; 500ug ; 1mg |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | 冷藏运输 |
| 背景说明 | Human Vascular endothelial growth factor receptor 2(KDR，VEGFR-2) is a member of the class III subfamily of receptor tyrosine kinases (RTKs).KDR is involved in a number of fundamental biological processes such as the regulation of angiogenesis，vascular development，vascular permeability，and embryonic hematopoiesis.It also plays an essential role in promoting proliferation，survival，migration and differentiation of endothelial cells，reorganization of the actin cytoskeleton.VEGFR2 is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors，whose expression is restricted to endothelial cells in vivo.The adaptor protein SHB has been shown to interact with VEGFR2 in receptor tyrosine kinase signaling.In addition，VEGFR2 is able to interact with HIV-1 extracellular Tat protein upon VEGF activation，and seems to enhance angiogenesis in Kaposi's sarcoma lesions.VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth，while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
