| 别名 | Fetuin-B;16G2;Fetuin-Like Protein IRL685;Gugu;FETUB |
| 英文名称 | Recombinant Human Fetuin B/FETUB |
| 中文名称 | Recombinant Human Fetuin B/FETUB |
| 规格 | 10ug ; 50ug ; 500ug ; 1mg |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | 冷藏运输 |
| 背景说明 | Fetuin-B is a member of the Fetuin family that is part of the Cystatin superfamily of Cysteine Protease inhibitors.It is reported that Fetuin-B is highly expressed in liver tissue,in tongue and placenta tissues.Fetuin-B is a paralogue of Fetuin-A.Fetuin-A and Fetuin-B display similarities and differences in their characteristics,however,they share only 20% amino acid sequence identity.The amounts of Fetuin-B in human serum,unlike Fetuin-A,vary with gender and are higher in females than in males.Fetuin-B is an inhibitor of basic calcium phosphate precipitation but is less active than Fetuin-A.Fetuin-B expression is decreased in Fetuin-A deficient knock-out mice.The expression of Fetuin-B has been shown to be regulated by FXR (Farnesoid X Receptor),a nuclear receptor activated by bile acids.Evidence has shown that overexpression of Fetuin-B in skin squamous carcinoma cells suppresses tumor growth in nude mice.The function of Fetuin B is still not fully characterized. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |