| 别名 | Tumor Necrosis Factor Receptor Superfamily member 5;B-Cell Surface Antigen CD40;Bp50;CD40L Receptor;CDw40;CD40;TNFRSF5 |
| 英文名称 | Recombinant Human CD40/TNFRSF5/CD40L receptor |
| 中文名称 | 重组人CD40/TNFRSF5/CD40L receptor |
| 规格 | 10ug ; 50ug ; 500ug ; 1mg |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
| 纯度 | ≥95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | 冷藏运输 |
| 背景说明 | CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily.CD40 is expressed in B cells，follicular dendritic cells，dendritic cells，activated monocytes，macrophages，endothelial cells，vascular smooth muscle cells，and several tumor cell lines.The extracellular domain of CD40 is characterized by Cysteine rich repeat regions.Interaction of CD40 with its ligand (CD40L) leads to aggregation of CD40 molecules，which in turn interact with cytoplasmic components to initiate signaling pathways.Several different TRAF proteins (adaptor proteins) have been identified to serves as mediators of the signal transduction.CD40 plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching，memory B cell development，and germinal center formation. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| 单位 | 支 |
