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| 规格编号 | 规格 | 库存 | 价格 |
|---|---|---|---|
| P01524-10ug | 10ug | 现货 | 1092.00 |
| P01524-50ug | 50ug | 现货 | 3276.00 |
| P01524-500ug | 500ug | 现货 | 14784.00 |
| P01524-1mg | 1mg | 现货 | 21120.00 |
| 别名 | Semaphorin-5A; Semaphorin-F; Sema F; SEMA5A; SEMAF |
| 英文名称 | Recombinant Human Semaphorin 5A/SEMA5A |
| 中文名称 | 重组人Semaphorin 5A/SEMA5A |
| 规格 | 10ug ; 50ug ; 500ug ; 1mg |
| 外观(性状) | Lyophilized from a 0.2 μm filtered solution of 20mM PB， 150mM NaCl， pH 7.4. |
| 溶解性 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE. |
| 储存条件 | Lyophilized protein should be stored at ≤ -20°C， stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 运输条件 | 冷冻运输 |
| Swiss Prot | Q13591 |
| 分子量 | 84.71 KDa |
| 表观分子量 | 100 KDa， reducing conditions |
| 区间范围 | Glu23-Thr765 |
| 背景说明 | Semaphorin-5A (SEMA5A) is a member of the Semaphorin family of axon guidance molecules. SEMA5A is a 140 kDa protein. Class 5 Semaphorins are type I transmembrane glycoproteins with an N- terminal Sema domain and multiple juxtamembrane type 1 Thrombospondin (TSP) repeats within their extracellular domains. SEMA5A is expressed in neuroepithelial cells surrounding retinal axons， oligodendrocytes， the base of limb buds， the mesoderm surrounding cranial vessels ， and the cardiac atrial septum and endocardial cushions， Human SEMA5A cDNA encodes a signal sequence， a extracellular domain (ECD)， a transmembrane sequence and an cytoplasmic portion. SEMA5A mutations have been implicated in the genetic syndrome，cri-du-chat，while some polymorphisms may increase risk for neurodegenerative diseases such as Parkinson. The expression of SEMA5A may be upregulated in metastatic cancer cells and downregulated in autism. |
| 来源 | Human Cells |
| 溶剂 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 内毒素 | < 1 EU/μg as determined by LAL test. |
| 标签信息 | C-6His |
| 单位 | 支 |
