| 英文名称 | Anti-UBP1 Polyclonal Antibody |
| 中文名称 | 上游结合蛋白1抗体 |
| 规格 | 100ul ; 50ul |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Mouse ; Human |
| 应用 | WB ; IHC-P |
| 稀释比例 | WB 1:200-1000. IHC-P 1:50-200. |
| 靶标 | UBP1 |
| 别名 | LBP 1a, Cp2b, DKFZp686L1745, LBP 1a, LBP 1B, LBP1, LBP1A, LBP1B, NF2d9, Upstream binding protein 1, Transcription factor LBP-1, UBIP1_HUMAN |
| 背景说明 | LBP1 (Upstream-binding protein 1), also designated UBP1, LBP1A or LBP1B, is a 540 amino acid protein that belongs to the grh/CP2 family (grainyhead transcription factor family). LBP1 is a transcriptional activator that regulates the placental expression of CYP11A1 and activates the Hemoglobin globin promoter in erythroid cells. LBP1 is responsible for repressing transcription of HIV-1 by binding to and preventing TFIID from interacting with its promoter region. Null expression of LBP1 causes uterine growth retardation in mice embryos suggesting a critical role in extraembryonic angiogenesis. |
| Swiss Prot | Q9NZI7 |
| Gene ID | 7342 |
| 亚细胞定位 | Nucleus |
| 研究领域 | 肿瘤&癌症 ; 信号传导 ; 表观遗传 |
| 免疫原 | A synthetic peptide of human UBP1 |
| 理论分子量 | 60kDa |
| 纯化方法 | Affinity purification |
| 储存液 | pH7.4 PBS,0.05% NaN3,40% Glycerol. |
| 储存条件 | Store at -20℃. Avoid freeze/thaw cycles. |
| 运输条件 | 冷冻运输 |
| 单位 | 支 |
| 属性分类 | 其他抗体 |