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| 规格编号 | 规格 | 库存 | 价格 |
|---|---|---|---|
| K009598P-50ul | 50ul | 2 | 2400.00 |
| K009598P-100ul | 100ul | 现货 | 3700.00 |
| 英文名称 | Anti-phospho-STAT3(Ser727)Polyclonal Antibody |
| 中文名称 | 信号传导与转录激活因子3抗体 |
| 规格 | 50ul ; 100ul |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 交叉反应 | Rat ; Human |
| 预测交叉反应 | Mouse;Chicken;Dog;Pig;Cow;Rabbit;Sheep;Guinea Pig |
| 应用 | IHC-P ; IF-C ; FCM |
| 稀释比例 | IHC-P 1:100-500. IF-C 1:100-500. FCM 0.2ug/Test. |
| 靶标 | phospho-STAT3(Ser727) |
| 别名 | STAT3 (phospho S727);p-STAT3 (phospho S727);STAT3(Phospho Ser727);STAT3(Phospho S727);p-STAT3(Ser727);Acute Phase Response Factor;APRF;DNA binding protein APRF |
| 背景说明 | Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity). |
| Swiss Prot | P40763 |
| Gene ID | 6774 |
| 亚细胞定位 | Cytoplasm Nucleus |
| 研究领域 | 免疫学 ; 细胞生物学 ; 心血管 ; 发育生物学 ; 信号传导 |
| 免疫原 | A synthetic peptide of human STAT3 around the phosphorylation site of Ser727 |
| 理论分子量 | 83/88kDa |
| 纯化方法 | Affinity purification |
| 储存液 | 0.01M TBS(pH7.4) with 1% BSA，0.03% Proclin300 and 50% Glycerol. |
| 储存条件 | Store at -20℃. Avoid freeze / thaw cycles. |
| 运输条件 | 冷冻运输 |
| 单位 | 支 |
| 属性分类 | 流式抗体 ; 修饰抗体 |
