Recombinant Human Proliferating Cell Nuclear Antigen 产品官方链接

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爱必信Absin
上海
2025-12-08 09:51

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爱必信(上海)生物科技有限公司
产品规格
规格编号规格库存价格
abs44071534-5ug5ug现货面议
abs44071534-25ug25ug现货面议
产品说明
    PCNA is located in the nucleus and is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer and helps elevate the processivity of leading strand synthesis during DNA replication. In reaction to DNA damage, PCNA is ubiquitinated and takes part in the RAD6-dependent DNA repair pathway. 2 transcript variants encoding the same protein have been found for PCNA gene. Pseudogenes of this PCNA gene have been described on chromosome 4 and on the X chromosome. PCNA is expressed during late G1- phase, S-phase of mitosis and persists until the end of the M-phase because of its long biological half-life. PCNA is induced by UV irradiation.
 
    PCNA Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 261 amino acids and having a molecular mass of 28769 Dalton.