总活性氧(reactive oxygen species,ROS)检测试剂盒(200)520 nm的试验
活性氧ROS检测试剂盒 促销价:2266元/200T
活性氧检测试剂盒说明书
RUO: For Research Use Only. Not for use in diagnostic procedures.
Description: The Total Reactive Oxygen Species (ROS) Assay Kit 520 nm contains the necessary regent and buffer for identifying ROS in cells by flow cytometry in the FITC channel. Reactive oxygen species are chemically reactive oxygen-containing molecules that are generated as a natural byproduct of the oxygen metabolism. ROS are constantly generated and eliminated under normal physiologic conditions and have important functions in cell signaling, homeostasis, and clearance of microbial infections. During times of environmental stress such as exposure to UV or heat, or during infection, ROS levels can increase dramatically leading to oxidative stress. Oxidative stress can result in damage to cellular proteins, lipids, and DNA, and has been linked to cardiovascular disease, cancer, diabetes, inflammation, and aging. Examples of ROS include superoxide ions and peroxides.
活性氧检测试剂盒参考文献 References: Freemerman AJ, Johnson AR, Sacks GN, Milner JJ, Kirk EL, Troester MA, Macintyre AN, Goraksha-Hicks P, Rathmell JC, Makowski L. Metabolic reprogramming of macrophages: glucose transporter (GLUT1)-mediated glucosemetabolism drives a pro- inflammatory phenotype. J Biol Chem. 2014 Feb 3.
Kramer PA, Ravi S, Chacko B, Johnson MS, Darley-Usmar VM. A review of the mitochondrial and glycolytic metabolism in human platelets and leukocytes: Implications for their use as bioenergetic biomarkers. Redox Biol. 2014 Jan 10;2:206-210.
Miletic AV, Graham DB, Montgrain V, Fujikawa K, Kloeppel T, Brim K, Weaver B, Schreiber R, Xavier R, Swat W. Vav proteins control MyD88-dependent oxidative burst. Blood. 2007 Apr 15;109(8):3360-8.
| Components | ROS Assay Stain Concentrate (lyophilzed powder): 1 x vial; store at less than or equal to -20 C. ROS Assay Buffer: 1 x 20 mL bottle; store at less than or equal to -20 C. |
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| Reported Applications | Flow Cytometric Analysis |
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