Acetyl Lysine Antibody

Catalog #ICP0380 Pack Size 100ug

Product Description： This pan-specific antibody is affinity purified using acetyl-lysine affinity chromatography. It recognizes proteins with acetylated lysine residues. The product can be utilized for proteomic studies of acetylated proteins and immunoaffinity chromatographic isolation of acetylated proteins/peptides from protease-digested proteins of whole cells. 
Species: Rabbit
Formulation: 250 μg/mL antibody in PBS, 50% glycerol
Immunogen: Acetylated KLH conjugates
Purification: Affinity chromatography with acetyl-lysine agarose.
Specificity: The antibody recognizes proteins acetylated on lysine residues. Tested: acetylated histone, acetylated BSA, and acetylated MBP.No cross-reaction to non-acetylated proteins.
Applications: ELISA; WB (1:1000); IP; Immunofluorescence; Immunochemistry
Scientific Description: DNA transcription cannot take place unless DNA is unwound from the nucleosomes. The cell unwinds the DNA by acetylating lysine residues within the proteins. It has been suggested that acetylation of non-histone proteins (e.g., transcription factors) and histones may be involved. Acetylation of these proteins may result in signal transduction within the chromatic domains.
Storage & Stability: Product is stable for several weeks at 4°C. For extended storage, store product at –20ºC. Expiration date is one year from date of shipping if properly stored. 

相关产品：
Acetyl Lysine Antibody，# ICP0380 ， ELISA,WB,IP,IHC,IF，￥3050，Immunechem

产品部分引用文献：

Referencefor Acetylated Lysine Antibodies (ICP0380)

Jing, E. et al. 2013. TheAmerican Diabetes Association. Doi: 10.2337/db12-1650 影响因子：

Foster, D.B. et al. 2013. PLoS ONE, 8 (7): e67513 影响因子：3.75

Lee, D.W. et al. 2013. Proteomics, 13 (15): 2278 - 2280 影响因子：4.132

Still, A.J. et al. 2013. The Journal of Biological Chemistry, 288:26209 -26219 影响因子： 4.651

Li, Y.Y. et al. 2013. The Journal of Biological Chemistry, 288:15537 -15546 影响因子：4.651

Vergnolle, O., Xu, H., and Blanchard, J.S. 2013. J. Biol. Chem.Doi: 10.1074/jbc.M113.495549 影响因子：4.651

Lee, D. and Goldberg, A.L. 2013. J. Biol., Chem. 1-12. Doi:10.1074/jbc.M113.489716 影响因子：4.651

Miao, Jun. et al. 2013. Molecular Microbiology, 89 (4): 660 - 675 影响因子： 4.961

Okanishi, H. et al. 2013. J. Proteome Res., 12 (9): 3952 -3968 影响因子： 5.056

Kalebic, N. et al. 2013. Mol. Cell. Biol., 33 (6): 1114-1123 影响因子： 5.372

Gentile, T.L. et al. 2013. Mol. Cell. Biol., 33 (19): 3864 - 3878 影响因子： 5.372

Jiang, H. et al. 2013. Nature, 496: 110 - 113 影响因子： 38.597

References for AntiAcetyl Lysine, Agarose (ICP0388)

Wagner, G.R. And Payne, R. M. 2013. The American Society forBiochemistry and Molecular

Biology. Doi: 10.1074/jbc.M113.486753 影响因子：

Choi, S. et al. 2013. Biochemical and Biophysical Researchcommunications,

435 (3): 403 - 407 影响因子： 2.4

Shin, B.H. et al. 2013. PLoS ONE, 8 (6): e64953 影响因子： 3.73

Miao, Jun. et al. 2013. Molecular Microbiology, 89 (4): 660 - 675 影响因子：4.961

Armour, S.M. et al. 2013. Molecular and Cellular Biology, 33 (8):1487 - 1502 影响因子：5.372

Masri, S. et al. 2013. Proceedings of the National Academy ofSciences, 110 (9): 3339 - 3344影响因子：9.737

Weinert, B.T. et al. 2013. Molecular Cell, 51 (2): 265 - 272 影响因子：15.28

Mertins, P. et al. 2013. Nature Methods, 10 (7): 634 - 637 影响因子：23.565

Reference for Asymmetric dimethylarginine (ICP0810) MonoMethyl Arginine Antibodies (ICP0801)

Low, J.K.K. et al. 2013. J.Proteome Res., 12 (9): 3884 - 3899 影响因子：5.065

Erce, M.A. et al. 2013. Proteomics, 13: 1059 - 1064 影响因子：4.132