Co(ii)/Cu(ii)-cocatalyzed oxidative C–H/N–H functionalization of benzamides with ketones: a facile route to isoindolin-1-ones†,10.1039/C9CC02661D

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Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

Co(ii)/Cu(ii)-cocatalyzed oxidative C–H/N–H functionalization of benzamides with ketones: a facile route to isoindolin-1-ones†

Xi Zhou,Hongyan Xu,Qiaodan Yang,Hua Chen,Shoufeng Wang,Huaiqing Zhao

Chemical Communications Pub Date : 06/13/2019 00:00:00 , DOI:10.1039/C9CC02661D

Abstract

A cobalt and copper catalyzed reaction protocol has been developed to achieve the oxidative C–H/N–H annulation of benzamides containing an 8-aminoquinoline moiety as the directing group with ketones. Structurally diverse isoindolin-1-ones were furnished by the reaction of various substituent benzamides with ketones.