Conjugate addition of radicals generated from diacyloxyiodobenzenes to dehydroamino acid derivatives; a synthesis of diaminopimelic acid analogues
John C. Vederas
Chemical Communications Pub Date : 01/24/2002 00:00:00 , DOI:10.1039/B109343F
Abstract

Radical decomposition of bis((2S)-N-benzyloxycarbonyl-2-aminopentan-5-carboxy-1-methyl ester)iodobenzene followed by decarboxylation and subsequent conjugate addition with a series of selectively protected dehydroamino acids leads to new analogues of diaminopimelic acid.