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CdSe/ZnS quantum dot–Cytochrome cbioconjugates for selective intracellular O2˙− sensing†
Da-Wei Li,Li-Xia Qin,Yang Li,Raheleh Partovi Nia,Yi-Tao Long,Hong-Yuan Chen
Chemical Communications Pub Date : 06/28/2011 00:00:00 , DOI:10.1039/C1CC13160E
Abstract

We demonstrate that the coupling system of negatively capped CdSe/ZnS QDs with an oxidized Cytochrome c (Cyt c) is capable of the fluorescent imaging of a superoxide radical (O2˙) with high sensitivity and specificity in living cells, without interference from other Reactive Oxygen Species (ROS) or relevant intracellular components.

Graphical abstract: CdSe/ZnS quantum dot–Cytochrome c bioconjugates for selective intracellular O2˙− sensing
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