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Biologically active diterpenes containing a gem-dimethylcyclopropane subunit: an intriguing source of PKC modulators†
María Jesús Durán-Peña,José Manuel Botubol Ares,Isidro G. Collado,Rosario Hernández-Galán
Natural Product Reports Pub Date : 05/21/2014 00:00:00 , DOI:10.1039/C4NP00008K
Abstract

Covering: 1973 to 2013

The biological activities of tigliane, lathyrane, ingenane, casbane, jatropholane and premyrsinane diterpenoids which contain the gem-dimethylcyclopropyl unit are described. Particular attention is given to their anti-viral, anti-microbial and cytotoxic activities. In the main text there are 132 references. The electronic supplementary information contains tables listing 424 of these diterpenoids, their occurrence and biological activity together with the references.

Graphical abstract: Biologically active diterpenes containing a gem-dimethylcyclopropane subunit: an intriguing source of PKC modulators
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