A direct access to bioactive fused N-heterocyclic acetic acid derivatives†,10.1039/C3OB42535E

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Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

A direct access to bioactive fused N-heterocyclic acetic acid derivatives†

Raju Adepu,A. Rajitha,Dipali Ahuja,Atul Kumar Sharma,B. Ramudu,Ravikumar Kapavarapu,Kishore V. L. Parsa,Manojit Pal

Organic & Biomolecular Chemistry Pub Date : 01/23/2014 00:00:00 , DOI:10.1039/C3OB42535E

Abstract

A Cu-catalyzed new sequence involving the Ullmann type intermolecular C–C followed by an intramolecular C–N coupling and then intramolecular aza-Michael type addition (and oxidation) in a single pot afforded various fused N-heterocyclic acetic acid derivatives as inhibitors of PDE4.