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Biomolecular release triggered by glucose input – bioelectronic coupling of sensing and actuating systems†
Shay Mailloux,Jan Halámek,Alexander Tokarev,Sergiy Minko,Evgeny Katz
Chemical Communications Pub Date : 04/09/2013 00:00:00 , DOI:10.1039/C3CC42027B
Abstract

A drug-mimicking release process was triggered by a glucose signal resulting in the formation of a negative potential on an electrode modified with PQQ-dependent glucose dehydrogenase. This electrode was coupled with another electrode coated with an Fe+3-crosslinked alginate polymer film, which was dissolved upon formation of the negative potential releasing entrapped species.

Graphical abstract: Biomolecular release triggered by glucose input – bioelectronic coupling of sensing and actuating systems
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