A direct catalytic ring expansion approach to o-fluoronaphthols and o/p-fluorophenols from indanones and 2-cyclopentenones†,10.1039/C5CC06825H

热搜：

Lactoyl-CoA 全氟丁基戊烷白叶藤碱全氟己基辛烷新白叶藤碱壳寡糖特色专题-生物多肽

A direct catalytic ring expansion approach to o-fluoronaphthols and o/p-fluorophenols from indanones and 2-cyclopentenones†

Jian Chang,Xiaoning Song,Wanqiao Huang,Dongsheng Zhu

Chemical Communications Pub Date : 09/03/2015 00:00:00 , DOI:10.1039/C5CC06825H

Abstract

A direct method for the synthesis of o-fluoronaphthols and o/p-fluorophenols has been developed by a catalytic ring expansion of indanones and 2-cyclopentenones, in which TMSCF₂Br was used as a unique :CF₂ source, a TMS transfer agent, as well as the Br⁻ and F⁻ releaser for the enolization, difluorocyclopropanation, desilylation, ring opening, defluorination, and aromatization sequence.