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Continuous flow of nitroso Diels–Alder reaction†
Erika Nakashima
Chemical Communications Pub Date : 06/24/2015 00:00:00 , DOI:10.1039/C5CC03458B
Abstract

Our flow reaction systems have provided quantitative yields of nitroso Diels–Alder products with no byproducts in cases of cyclic dienes without temperature and pressure controls. Additionally, the reaction times were significantly shortened by using homogeneous catalyst (CuCl) or heterogeneous reagent (MnO2) in comparison with batch reaction.

Graphical abstract: Continuous flow of nitroso Diels–Alder reaction
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