Copper-catalyzed trifluoromethylation of aryl boronic acids using a CF3+ reagent†
Jun Xu,Dong-Fen Luo,Bin Xiao,Zhao-Jing Liu,Tian-Jun Gong,Yao Fu,Lei Liu
Chemical Communications Pub Date : 03/07/2011 00:00:00 , DOI:10.1039/C1CC10359H
Abstract

A copper-catalyzed process for trifluoromethylation of aryl, heteroaryl, and vinyl boronic acids has been developed. The reaction is conducted under mild conditions and shows tolerance to moisture and a variety of functional groups.

Graphical abstract: Copper-catalyzed trifluoromethylation of aryl boronic acids using a CF3+ reagent