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Designing a simple organic salt-based supramolecular topical gel capable of displaying in vivo self-delivery application†
Joydeb Majumder,Jolly Deb,Mahua Rani Das,Siddhartha Sankar Jana,Parthasarathi Dastidar
Chemical Communications Pub Date : 12/04/2013 00:00:00 , DOI:10.1039/C3CC48513G
Abstract

The supramolecular synthon approach has been exploited to design simple salt-based supramolecular gelators derived from a non-steroidal anti-inflammatory drug (NSAID) – naproxen; one such biocompatible anti-inflammatory gelator salt was converted into a topical gel that showed excellent in vivo self-delivery application in treating imiquimod (IMQ)-induced skin inflammation in mice.

Graphical abstract: Designing a simple organic salt-based supramolecular topical gel capable of displaying in vivo self-delivery application
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