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Copper-mediated sulfonylation of aryl iodides and bromides with arylsulfonyl hydrazides in PEG-400†
Xiangmei Wu,Yan Wang
New Journal of Chemistry Pub Date : 05/21/2018 00:00:00 , DOI:10.1039/C8NJ00075A
Abstract

Sulfonylation using stable and readily available arylsulfonyl hydrazides and aryl iodides or bromides mediated by cupric acetate has been achieved. Using polyethylene glycol (PEG-400) as an eco-friendly medium, the coupling reaction could afford a series of unsymmetrical diaryl sulfones in moderate to good yields without the presence of additional ligands and base.

Graphical abstract: Copper-mediated sulfonylation of aryl iodides and bromides with arylsulfonyl hydrazides in PEG-400
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